Caesarea, Israel – September 1, 2021 – IceCure Medical Ltd., NASDAQ: ICCM and TASE: ICCM, developer of next-generation minimally invasive cryoablation technology that destroys tumors by freezing them, announced that it has signed its first distribution agreement with Mutlu Medikim Tıbbi Malzemeleri Tic. A.Ş. for the sale of the ProSense™ Cryoablation System and probes in Turkey. A long-term exclusive distribution agreement is expected within twelve months of the agreement.

“This agreement opens a significant market opportunity for the ProSense™ Cryoablation System in Turkey. Turkey has a well-developed healthcare system supporting a population of over 80 million,” said Eyal Shamir, CEO of IceCure. “This first distribution agreement expands our regulatory and commercialization activities in the Middle East, Europe, Asia and Latin America.”

“We are excited to bring IceCure’s innovative cryoablation technology to Turkey,” said Cezmi Mutlu, Founder and President of Mutlu Medikim Inc. “As a well-established distributor of global medical products, we believe this system has great potential in the interventional oncology market.”

Under the initial distribution agreement, Mutlu Medikim Inc. will be responsible for all sales processes in Turkey and will place its first order for approximately $100,000.

ABOUT ICECURE MEDICAL
Founded in 2006, Israel-based IceCure Medical develops and markets advanced cryoablation systems that freeze tumors (benign and cancerous). Its primary targets are breast, kidney, bone and lung cancer. Its minimally invasive technology offers a safe and effective alternative to surgery in the hospital. The system, which has FDA and CE approvals, is marketed worldwide.

ABOUT MUTLU MEDİKİM A.Ş.
Based in Istanbul, Mutlu Medikim A.Ş. is part of a medical device distributor group that includes companies such as Opakim and MDS, and generated approximately $30 million in revenue in 2020. Founded in 1980, the company aims to be a major player in the Turkish market by focusing on interventional and IVD products.

FORWARD-LOOKING STATEMENTS
This press release contains forward-looking statements within the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Expressions such as “expects,” “anticipates,” “plans,” “believes” and similar expressions indicate future expectations. Actual results, performance and achievements may differ due to risk factors in the filings with the SEC at www.sec.gov.uk/index.php?topic=10 ...

Breast cancer may not show symptoms until it reaches advanced stages. Early diagnosis of breast cancer increases the chances of successful treatment and survival. The most important factor in early diagnosis is the person's awareness of this issue. The following methods are applied for early diagnosis:

• Between the ages of 20-40: Self-breast examination should be done once a month. When one of the breast cancer symptoms is seen, a doctor should be consulted immediately. In addition, a doctor should be visited for a breast examination every two years.
• Between the ages of 40-69; Self-breast examination should be done once a month, a doctor should be visited for a breast examination every year, and a mammogram should be taken every two years. Mammograms are taken free of charge at Cancer Early Diagnosis, Screening and Education Centers (KETEM) in every province in our country; and self-breast examination trainings and brochures are also provided free of charge.

Treatment
Each patient's treatment varies; multiple factors such as the location of the disease, its stage, the patient's age and other health problems are effective in the treatment decision. Different treatment options such as surgery, radiation therapy (radiotherapy) and drug therapy (chemotherapy) are applied in breast cancer.

Prevention
As with all cancers; healthy (rich in vegetables and fruits) eating habits, doing at least 150 minutes of moderate (at least 10 minutes of brisk walking, cycling, etc.) or at least 75 minutes of vigorous (at least 10 minutes of running, swimming, etc.) physical activity per week, being at a healthy weight and staying at that weight reduce the risk of breast cancer. You can learn whether you are at a healthy weight by consulting your family doctor. There are studies that breastfeeding for 1.5-2 years protects mothers from breast cancer.

We participated in the 2nd Interventional Oncology: Multidisciplinary Treatment Approach Meeting held in Ankara between December 17-19 with the team of Mutlu Medikim, IceCure Medical and our authorized dealer Baturalp Medical. We made demo studies with the IceCure ProSense device used in cryoablation treatment. Our stand was highly attended by both our professors and companies.